Effects of Yixin Oral Liquid on Myocardial Infarct Size and Hemorheology in Rats with Acute Myocardial Ischemia

Abstract:

Effect of Yixin oral liquid on Tnyocardial infarct size and hemorheology were studied in rats with acute myocardial ischemia,The results showed that the liquid at a dosage of 8 or 16g/kg,ig×5d could significantly reduce the size of myocardial infarcts and decline serum CK and LDH activities at 24h after ligation of LAD. It could also decrease ηBH、ηBL、ηBHR、ηBLR、ηP、ERI、RCET、whereas HCT、Fib、ESR and EEC were not changed markedly.Yixin at a dosage of 4g/kg had no significant effects on the above parameters.