Abstract:Morphometric techniques,RIA and histochemical techniques were applied to study effect of the anti-hepatic fibrosis by Pinggansan Granule.The results showed that the percentage of the area full of reticular fiber in affected location was smaller than that of control group,the perimeter,long and short diameter of the egg granuloma in the experimental mice was decreased.And PC-Ⅲ,PC-Ⅰ and HYp in the drug-treated group was decreased.