Effect of Qifu Tang(QFT)on Activity of Macrophage(Mφ)and Mediation in Mice with Deficiency of Vital Function

Abstract:

To investigate the mechanism of promoting vital function of QFT is the purpose of our experiment.QFT was orally respectively administrated normal and abnormal mice with Deficiency of Vital Function (DVF) induced by hydrocortisone(HC) for 14 days and the activity of celiac Mφ,mediates and enzymes were detected.The results showed that QFT could evidently improve the activity of celiac Mφ in normal mice,especially in mice with DVF.In mice with DVF,QFT could decrease the formation of NO,promote Mφ to secrete IL1 and TNF,increase arginase and SOD activities in celiac Mφ.In normal mice,QFT could also promote Mφ to secrete TNF and inhibit SOD activity in celiac Mφ.