Abstract:To observe the nourishing Yin action of Six-Ingredient Rehamnnia Pill (SIRP),Thyroxin (ig) was orally administrated to rats for 3 weeks in order to induce kidney yin-deficiency model of rats.Results showed SIRP markedly decreased the heart rate,plasma viscosity,serum T3 and T4,copper,the ratio of copper to zinc,and the intake of water,increased urine output,body weight,blood sugar,pain threshold,Index of thyroid and serum IgG contents.The dose-dependent relationship was significant.SIRP showed significant nourishing Yin action on kidney yin-deficiency rats induced by hyperthyrea.