Experimental Study of Jiangni Decoction on Rat with Chronic Renal Functional Failure

Abstract:

To observed the therapeutically effects of Jiangni Decoction (JND) on chronic renal functional failure (CRF) induced by adenine in rat. Sprague-Dawley rats fed balance diet containing 0.4% adenine for 4 weeks. We respectively determines the content of the Middle molecular substances (MMS) in serum and the excretion of urinary β-D-Galactosidase (GAL-ase) after treatment with JND. Compared with the pathological model group, the content of MMS in serum and excretion of GAL-ase in urine were markedly decreased in the JND group. The results showed that JND may play an important role in the improvement of rat with CRF.