Abstract:It was introduced for new progression of chemical component and pgarmacological studies on main chemical fractions of Radix Bupleuri in recent ten years.Saikosaponin k,l,m,n,q,t,were discovered lately.Through the pharmacological studies on main chemical fractions,saikosaponin could inhibite the activity of trypsin,regulate immunity,and treat nephrosis and insomnia.The mechanisms of these actions were studied.Through farther separated studies of polysaccharide of Radix Bupleuri,the possible active fractions were brought forward.It provides the background for the new drug study of gastric mucosa protection and immunoloregulation.New prospect was showed for the application of Radix bupleuri because of double action to adenylate cyclase (AC) of the extracts of Radix Bupleuri.