Abstract:To investigate the effect of Yiqi Huoxue Prescription on lipid,haemorheology,lipid peroxide (LPO),nitric oxide (NO) in the experimental hyperlipidemia rats,a hyperlipidemia rat model was established by feeding high Lipid diet.The rats were randomly divided by body weight and the level of blood lipid.After 6 weeks,blood samples and livers were collected and determined as above.Results showed Yiqi Huoxue Prescription can effectively decrease the level of TG TC LDL-C and raise the level of HDL-C in the experimental hyperlipidemia rats compared with the model group.Yiqi Huoxue Prescription can also decrease the haemorheologcal parameters,decrease the total viscosity,blood plasma viscosity,hemaocrit and the content of fibrinogen.Yiqi Huoxue Prescription can reduce the lipid peroxide and reduce the content of MDA in liver.Yiqi Huoxue Prescription can increase the content of NO in blood plasma and decrease the endothelial injury and protect the endothelial function.