Abstract:Objective To investigate the effects of assemble flavones of Fortune's drynaria rhizoma on animal bone mineral density,phasma calcium and phosphorus, and on analgesia action.Methods Wistar rat and Kunming mouse were used as experimental animals. Osteoporosis was induced by orally given retinoic acid(70 mg·kg-1·d-1) to the rats for 14 dasy. For evaluation of analgesia action,body wresting was induced by vinegar id injection in the mice, and hot plate method(55℃) of mouse was employed. Results Bone mineral density and plasma calcium were significantly increased for the dose groups of Fortune's drynaria zhizoma compared with the control(P<0.05).Analgesia action evaluated by vinegar induced and heat induced pain was also significant compared with the control(P<0.05).Conclusion The assemble flavones of Fortune's drynaria rhizoma have the functions of elevating blood calcium, increasing bone mineral density and analgesia action.
