Abstract:Objective:observe the effect of Guben Zhike Gao on expelling phlegm,relieving coungh and asthma and resisting inflammation.Methods:The coungh-relieving effect of Guben Zhike Gao was observed by mouse cough model induced by SO2 and NH4OH with Capillary method. Observation on the phlegmexpelling effect was completed by using phenol red. Observation on the asthma-relieving effect was completed by inducing asthma with Ach-histamine method in quinea pig. The anti-inflammation effect of Guben Zhike Gao was investigated by implantation of carrageenin and cotton ball in rat. Results:The Guben Zhike Gao can prolong apparently the coughing incubation period and reduce coughing frequency;increase excretion of phenol red and phlegm from the respiratory tract; prolong the incubation period of asthma due to Ach-histamine solution and resist inflammation on acute and chronic inflammator models. Conclutions:The Guben Zhike Gao has the functions of expelling phlegm,relieving cough and asthma,resisting inflammation.
