Abstract:Objective:To explore quality of Gardeniae Fructus from Bazhong. Method: HPLC and ELSD were used to determine the content of geniposide, crocinⅠ,and ursolic acid. Using t-test and Z-score comprehensive evaluation on quality of Gardeniae Fructus from Bazhong. Result: Results of t- test showed that the content of Geniposide in Gardeniae Fructus from Bazhong is significantly higher than in Gardeniae Fructus from Hubei(P<0.05), outstandingly higher than in Gardeniae Fructus from Jiangxi or Jiangjin(P<0.001); the content of crocinⅠand ursolic acid in Gardeniae Fructus from Bazhong was remarkablly higher than in Gardeniae Fructus from Hubei or Jiangxi or Jiangjin(P<0.001); we established multiple linear regression equation between Z-score and ratios of geniposide, crocinⅠ,ursolic acid, geniposide X1, crocinⅠ X2 and ursolic acid X3, respectively. the multiple linear regression equation was Z=-11.213 6+0.0218 2X1+0.560 2X2+17.331 6X3(R2=0.999 9). Results of Z-score comprehensive evaluation showed that Z-score of Gardeniae Fructus from Bazhong is far ahead of Gardeniae Fructus from Hubei or Jiangxi or Jiangjin. Conclusion: Quality of Gardeniae Fructus from Bazhong is very good;Gardeniae Fructus from Bazhong is well worth focusing by government and society.