Abstract:Objective:Study on the chemical constituents from Cibotium barometz and their scavenging activities for 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical. Method: The chemical constituent from70% alcohol extract of C. barometz was isolated on chromatograph of silica gel and sephadex LH-20 and HPLC, their structure were elucidated on the basis of spectra data and the compounds were tested for their scavenging activities on DPPH radical. Result: Ten compounds were purified and their structure were identified as 1-O-caffeyl-D-glucopyranose ( 1 ), 6-O-caffeyl-D-glucopyranose ( 2 ), 3-O-caffeyl-D-glucopyranose ( 3 ), 3-hydroxymethyl-2(5H)-furanone ( 4 ), β-miroside( 5 ), cibotiumbaroside A( 6 ), protocatechuic acid ( 7 ), glucose ( 8 ), mannose ( 9 ), Corchoionoside C ( 10 ), kojic acid ( 11 ). Three isolated compounds showed strong scavenging activities on DPPH radical. Conclusion: Compound 1-5 were isolated for the first time from C. barometz. among of them, compound 1 , compound 3 and compound 6 showed significant antioxidant activity, and the scavenging activity of compound 1 was similar to that of Vit C.
