Abstract:Objective:To investigate the clinical effect of Bushen Huoxue Tongluo capsule(BHTC) combided with western mediciine on patitents with Parkinson's disease (PD). Method: One hundred and twenty PD patients were entorlled in the randomized control tiral (RCT). The patients were randomly divided into two groups (60 each): treatment group (BHTC and western medicine,peros) and control group (wetern medicine only, peros). At the end of the third month, he unified parkinson disease rating scale (UPDRS) and quality of life of Parkinson's disease rating scale (PDQ) were compared respectively for each group by a neurology doctor on the time of pre-treatment and one month, two months and three months post-treatment to record mental, behavioral and emotional state (UPDRS-Ⅰ), daily activities (UPDRS-Ⅱ), motor function check (UPDRS-Ⅳ), motor complications(UPDRS-Ⅳ), improvement of motor function (LSIB) and Parkinson's disease life quality rating scale (PDQ). Result: The study established a comprehensive treatment program for Parkinson's disease. After one month, two months and three months treatment, the effective power was significantly highter in treatment group than in control group (P<0.05). Conclusion: BHTC has an obvious effect on PD patients. BHTC combined with western medicine can improve motor function and daily living activity in PD patients better than western medicine only.