Abstract:Objective: To optimize processing technology of Atractylodes macrocephala frying with bran. Method: With the content of atractylenolide Ⅰ,atractylenolide Ⅱ,atractylenolide Ⅲ and atractylone as indexes,which were determined by HPLC,effects of frying temperature,frying time and the amount of bran on processing technology was investigated by L9(34) orthogonal test,in order to determine the best technology. Result: Optimum processing technology was as following:frying temperature 170 ℃,frying time 2 min,the amount of bran 10%. Conclusion: This optimized processing technology was stable and practicable.