Effect of Pinelliae Rhizoma and Fritillariae Thunbergli Bulbus on Antioxidant Activity of Wutou Decoction

Abstract:

Objective: The effect of Pinelliae Rhizoma and Fritillariae Thunbergli Bulbus on antioxidant activity of Wutou decoction (WTD) was studied to validate the scientific of aconite incompatibility. Method: The total antioxidant activity of different samples was determined by ferric reducing antioxidant power (FRAP) assay and DPPH·scavenging assay. The different antioxidant activities of WTD were compared to the WTD added with Pinelliae Rhizoma (RP) and Sichuan fritillary (SF) respectively. Moreover, the antioxidant activities of Monkshood Prepared (PM), PM with opposing herbal remedies and PM with the other herb medicine in WTD. Result: The antioxidant activities of WTD were inhibited by RP and SF. The inhibition activity of SF was more obviously. In the combination between WTD and ZF or PM and ZF, the total antioxidant activity was both enhanced. Conclusion: The antioxidant activities were decreased in the combination between WTD and RP or WTD and SF.