Clinical Effects of Yifei Capsule plus Tankejing Powder on Stable-stage Patients with Chronic Obstructive Pulmonary Disease

Abstract:

Objective: To observe the clinical effects of Yifei capsule plus Tankejing powder on stable-stage patients with chronic obstructive pulmonary disease (COPD). Method: Ninety-eight subjects were randomly divided into observation group and control group (n=49 each). Both groups were adopted the conventional non-drug therapy, and were given drugs used for dissolveing sputum and antispasmodic on demand. The observation group was given Yifei capsule, 4 capsules tid, all for 12 days. Tankejing powder (0.2 g each time, 3-6 times daily) was given when abundance of phlegm and heavier cough occurred. The lung function, St George's respiratory disease questionnaire (SGRQ) and BODE index were measured to evaluated the quality of life. Result: The observation group showed significant improvement compared with the control group in the following indexes: forced expiratory volume in first second (FEV₁), the ratio of FEV₁ and forced vital capacity. There was significant difference between the two groups (P<0.05). The scores of SGRQ and the three dimensions of respiratory symptoms, activity and the affects of disease in the observation group were more lower than those in the control group (P<0.05). The scores of the three dimensions of FEV₁, modified medical research council scale (mMRC) and 6 min walking distance (6 MWD) and BODE index were more lower than those in the control group (P<0.05). Conclusion: Yifei capsule plus Tankejing powder can significantly improve the lung function, clinical symptoms and BODE index in patients with COPD, and it can significantly improve the quality of life for patients.