Clinical Effects of Xuebijing Injection on Treatment of Patients with Old Hypostatic Pneumonia

Abstract:

Objective: To observe the clinical effects of Xuebijing injection on the treatment of patients with old hypostatic pneumonia. Method: Sixty-four subjects were randomly divided into observation group and control group (n=32 each). The control group was given 1.5 g drugs combined with cefoperazone sodium and sulbactam (2:1), which were diluted by 100 mL 5% glucose injection (bid); and they were given ambroxol hydrochloride injection which contained 30 mg ambroxol hydrochloride diluted by 100 mL normal saline meanwhile (bid). On the basis of the control group intervention, the treatment group was given 50 mL Xuebijing injection diluted by 100 mL normal saline by intravenous drip (bid). All the intervention in two groups lasted 14 days. Cough and expectoration, body temperature, blood picture and lung condition by X-ray were observed. Result: The total symptom scores of the observation group in the 4, 7 and 14 day were lower than those in the control group (P<0.05, P<0.01).In the observation group, the time for body temperature to restore normal, cough and expectoration disappeared time, the time for lung to restore normal and the time for blood picture back to normal were less than those in control group (P<0.05). The clinical effects of the observation group were superior than that of control group (P<0.05). Conclusion: Xuebijing injection can significantly improve clinical signs and symptoms for patients with old hypostatic pneumonia and enhance clinical effects so as to promote the recovery of disease.