Abstract:Objective: To observe the clinical effects of Yunnan Baiyao for promoting postoperative rehabilitation of cervical intraepithelial neoplasia by cold knife conization (CKC). Method: Ninety-six postoperatives of cervical intraepithelial neoplasia Ⅲ by CKC were randomly divided into observation group and control group (n=48 each). CKC postoperative wound was fulgerized and packed with gauze strip for the control group and conventional anti-infection treatment was given for 4 days; CKC postoperative wound was fulgerized and covered with Yunnan Baiyao powder and packed with gauze strip for the observation group and conventional anti-infection treatment was given for 4 days. Yunnan Baiyao capsule was added to the observation group, 2 softgels each time, tid, all for 5 days. Postoperative vaginal drainage time, drainage quantity, vaginal bleeding time, amount of bleeding, decrustation of cervical scab and cervical wound healing was observed in 1, 2,5,8 weeks. Result: Postoperative vaginal bleeding time and average amount of bleeding of the observation group were lower than the control group (P<0.01); Postoperative vaginal drainage time and average drainage quantity in the observation group were lower than those in control group (P<0.01). For the observation group, there was 23 cases after operating 5 weeks and 45 cases after operating 8 weeks of wound healing which were superior to 12 cases and 34 cases of the same period in the control group (P<0.05). Cleaning degree of vagina after 5 weeks in the observation group was obviously superior to the control group (P<0.01); there was no obvious difference between the curative effect of the two groups. Conclusion: Postoperatives of cervical intraepithelial neoplasia Ⅲ by CKC treated with electrocautery and covered wound with Yunnan Baiyao powder, and supplemented with Yunnan Baiyao capsule orally could reduce postoperative complications and promote recovery.