Effect of Aidi Injecttion on the Cytokine Expression of Radiotherapy for Lung Cancer

Abstract:

Objective: It is to explore the effect of Aidi Injecttion on the expression of radiotherapy for lung cancer patients. Method: Fourty cases of lung cancer were randomly divided into treatment group (20 cases) and control group (20 cases).The two groups were given three-dimensional conformal radiation therapy (3D CRT).Meanwhile,the treatment group was added Aidi injecttio.There were some indices compared before and after radiotherapy including the serum interleukin-6(IL-6), the tumor necrosis factor-α(TNF-α) and the transforming growth factor-β(TGF-β).And then,the incidence of the radiation pneumonia were also compared between two groups. Result: After the end of treatment,the IL-6, the TNF-α and the TGF-β of the treatment group were lower than those of the control group. There was significant difference(P<0.05). Nevertheless there were no significat differences between two groups about incidence of the radiation pneumonitis. Conclusion: Aidi injecttion could relieve the progress of Radiation pneumonitis through decreasing levels of the IL-6,the TNF-α and the TGF-β,thus,prevention of the occurrence of radiation pneumonia.