Abstract:Objective: To comparative analysis flurbiprofen ester joint sufentanil, and used alone sufentanil, in the patients after intestinal surgery produced by the analgesic effect and metabolic toning effect. Method: Will be in february 2011-July 2012 received intestinal cancer radical operation of 80 patients as experimental investigation of the sample, random divided into sufentanil analgesic group (group A, n=40) and fluorine than flurbiprofen ester joint sufentanil analgesic group (group B, n=40). Due to A, B group of patients after surgery after 3 days shall not eat, can only through the week intravenous nutrition supplement. In this time logging A, B group of patients in the stage of fast the tumor necrosis factor-α(TNF-α), body temperature numerical, cortisol, nitrogen balance, the integral effect of analgesia, interleukin-6(IL-6) and adrenal line changes. Result: The two groups of analgesic score difference was statistically significant. In the third day A, B group compared with patients who the analgesic effect of 1 day all appeared obviously improved. Postoperative body temperature, negative nitrogen balance, TNF-α and IL-6 change group B than a group obviously. But adrenaline numerical and cortex leaven numerical and no apparent change. Conclusion: Compared with the use of a single sufentanil on postoperative analgesia, sufentanil and flurbiprofen ester mixed analgesic effect and no obvious advantages, but sufentanil and flurbiprofen ester mixture can play a good postoperative conditioning effect.