Investigation of Comprehensive Evaluation for Traditional Chinese Medicine Preparations Based on Principal Component Analysis

Abstract:

Objective: To Establish comprehensive evaluation model of production process of Qingre Jiedu oral liquid,and apply to production monitoring of this preparation. Method: Qingre Jiedu oral liquid was selected as study object,with shared peaks as multivariate variables,principal component analysis,factor analysis and other methods were adopted to achieve data compression and interpretation,and the overall quality changes of preparations was revealed by a small amount of principle component analysis. Result: Optimum extraction technology of Qingre Jiedu oral liquid was:extracted 2 times with 10 times the amount of water,100 min per time. Conclusion: Dimensionality reduction analysis could simplify analysis process and reveal inherent laws of raw data penetratingly,it was suitable for control of the overall quality of traditional Chinese medicine.