Abstract:Objective: To investigate effects of moisture content on quality of decocted extract and determine its quality guarantee period. Method: Decocted extract was prepared by traditional concentrated process,moisture content was determined,according to microbial limit test method from the appendix XIII C in 2010 edition of 'China Pharmacopoeia',examination for effects of moisture content on microbiology of pastes was adopted. Result: Moisture content had significant effects on microbiology of decocted extract,with increasing of moisture content,bacterial colonies would appear,stability of decocted extract decreased. Conclusion: By controlling moisture content strictly,we could avoid decocted extract becoming mildew,harden and other phenomenon,then quality of decocted extract was ensured and its quality guarantee period was extended.