Abstract:Objective: To investigate effects of factors on stability of five-dimensional lysine oral solution. Method: With content changes of vitamin C as index,single factor tests were adopted to investigate influence of antioxidants,water and pH to stability of five-dimensional lysine oral liquid. Result: The content of vitamin C in five-dimensional lysine oral solution plus antioxidants was higher than the blank heating group without antioxidants,adding single antioxidant was higher than adding composite antioxidant,content changes was large before and after heating.The boiling water group was stable by comparing with the often water group.Stability of prepared oral liquid weakened by increasing of pH. Conclusion: Stability of five-dimensional lysine oral solution was fine by adding antioxidants with boil water and pH 3.6.