Analysis of Cleansing Mechanism of Aconitum kusnezoffii

Abstract:

Objective: To analyze cleansing mechanism of Aconitum kusnezoffii. Method: HPLC was adopted to determine the content of mesaconine,aconitine,hypaconitine,benzoylmesaconine,benzoylaconitine,benzoylhypaconitine in A. kusnezoffii with stems,A. kusnezoffii without stems and stems of A. kusnezoffii. Result: The total content of three kind of diester alkaloids in A. kusnezoffii with stems,A. kusnezoffii without stems and stems of A. kusnezoffii was 0.59%-0.66%,0.61%-0.69%,0.39%-0.42%,respectively;The total content of three kind of monoester alkaloids was 0.09%-0.10%,0.09%-0.12%,0.06%-0.08%,respectively.Except six alkaloids chromatographic peaks,there was another common peak(peak 4),area of peak 4 in stems of A. kusnezoffii was 55%-80% to that in A. kusnezoffii without stems. Conclusion: Content of six alkaloids was found in A. kusnezoffii without stems and stems of A. kusnezoffii was different.Stems of A. kusnezoffii was the non-medicinal parts whose content of six alkaloids was low,it could be removed.