Abstract:Objective: To investigate the clinical efficacy of Tingli Dazao Xiefei decoction and Daotan soup on the Tanyu Zufei type lung cancer. Method: The one hundred cases of Tanyu Zufei type lung cancer in middle and late period were randomly divided into control group and treatment group, 50 case. each group. The control group only used western medicine according to chemotherapy scheme, and the treatment groups were treated with lung cancer prescription based on the treatment of control group. After 3 months,the short term curative effect, the improvement of life quality, the changes of body weight, the improvement of peripheral blood and immune function, and the occurrence of adverse reaction and the survival rates of patients after 1,3 and 5 years' treatment were observed. Result: The total effectiveness in control group and treatment group was 80.0% and 50.0%,respectively,the short term curative effect in treatment group was better than the control group, and there was significant difference(P<0.05);the improvement rate of life quality was 70.0% and 40.0%, respectively,the treatment group was better than the control group, and there was significant difference(P<0.05);the improvement rate of body weight was 16.0% and 20.0%, respectively, and there was no significant difference; the peripheral blood abnormality rates of treatment group was obviously lower than the control group, and there was significant difference(P<0.05);the treatment and control group were compared before and after treatment, the immune indexes (CD4+,CD8+,CD4+/CD8+and the activity of NK cell) all presented significant difference of different degree(P<0.05 and P<0.01),and the immunity of treatment group was obviously improved; compared with control group, the occurrence rate of adverse reaction in treatment group was obviously lower than control group, and there was significant difference(P<0.05). The survival rates of patients after 1, 3 and 5 years' treatment was better than the control group, and there was significant difference(P<0.05). Conclusion: The tanyuzufei type lung cancer was cured bylung cancer prescription combined with chemotherapy, and it could effectively relieve the clinical symptoms, improve the immunity, reduce the occurrence of adverse reaction, and improve the life quality, and the traditional Chinese medicine combined with chemotherapy has the efficacy and low toxicity.
