Abstract:Objective: To investigate the effect of rosuvastatin combined with Qizhi Tongluo capsule to high-sensitivity C-reactive protein (hs-CRP)in acute cerebral infarction patients with normal cholesterol, as well as its clinical efficacy. Method: Ninty-eight patients were selected and divided randomly into a control group(n=49) and a treatment group(n=49). Patients in the control group were received 10 mg rosuvastatin calcium tablet treatment every day and others in the treatment group were added 0.2 g Qizhi Tongluo capsule 2 times a day based on foundation treatment. Result: hs-CRP levels and neural function defect scales of two groups on the 8th day and the 15th day after treatments were different. The differences were considered statistically significant, respectively, for P<0.05 and P<0.01.The total effective rates of two groups on the 15th day after treatments were respectively 81.6% and 95.9%(P<0.05).Briefly,compared with the control group, hs-CRP levels and neural function defect scales in patients in the treatment group were lower,but the total effective rate was higher. Conclusion: Combination of rosuvastatin and Qizhi Tongluo capsule in acute cerebral infarction patients with normal cholesterol can promote neural function recovery,which is better than that of alone rosuvastatin.