Zhisou San in Treatting Coughi Induced by Infections Based on Randomized Clinical Trials-Meta-analysis

Abstract:

Objective: A systematic review on treatment of infections by Zhisou san was carried out.Method: Meta-analysis of randomized controlled trial (RCT) was used,and RevMan 5.1 software for statistical analysis was adopted.Result: A total of 24 published RCT (n=2 147) was included,which was divided into the experimental group of 1 087 cases and the control group of 1 060 cases. In simple Zhisou san and western medicine groups the combined OR of cure rate of the group fixed effects model was 3.71, 95% CI[2.96,4.66], P<0.000 01; In Zhisou san combined with western medicine and western medicine, OR was 2.76,95% CI[1.98,3.85, P<0.000 01.The combined OR of Zhisou san was 7.90, 95% CI[5.67,11.01], P<0.000 01; OR of Zhisou san combined with Western medicine. Western medicine was 3.62,95% CI[2.22,5.92], P<0.000 01.Conclusion: Zhisou san in treating infections may be effective, but the further confirmation by high-quality research trials was needed.