Study on the Polysaccharide of the Branch and Leaf of Folk Medicine Agastache rugosa Obtained from Qinba Mountain

Abstract:

Objective: Agastache rugosa polysaccharide was extracted from the branches and leaves of A. rugosa, the research can provide and supply scientific basis for the search of its polysaccharide antioxidant activity to empolder A. rugosa medicinal materials. Method: The polysaccharide was obtained from A. rugosa branches and leaves by ultrasonic extraction method, and tested L₉(3⁴) orthogonal experiment on the base of material-liquid ratio, ultrasonic time and pH value, to optimize A. rugosa polysaccharide extract technology;A. rugosa polysaccharide to remove hydroxyl radical was also studied. Result: The best A. rugosa polysaccharide extracting technology assisted by ultrasonic was material-liquid ratio 1:10, ultrasonic time 30 min, and pH value 6, and the extraction rate of polysaccharide was reached up to 7.50%. A. rugosa polysaccharide had significant scavenging effect for hydroxyl radical produced by Fenton reaction theory. Conclusion: A. rugosa polysaccharide had antioxidant activity. The polysaccharide may be extracted from the branches and leaves of A. rugosa, and had development value.