Guben Pingchuan Decoction Treatment on 48 Cases of Chronicity-persistent Period in Bronchial Asthma

Abstract:

Objective: To investigate the effect of Guben Pingchuan decoction treatment of chronicity-persistent period in bronchial asthma. Method: Niety-six patients were randomly allocated into observational group and control group, 48 cases in each. With the reference of bronchial asthma prevention and treatment guidelines (2008) for conventional treatment, the observation group was treated with Guben Pingchuan decoction, 1 times/day, lasting for 12 weeks. Pre and post the treatment, asthma control test (ACT) scores, lung function forced expiratory volume in one second(FEV₁), forcedvitaclcapacity(FVC), expiratory flow ratel(PEF), asthma symptom score, quality of life assessment and symptom scales of lung and kidney Qi deficiency with cold phlegm were measured. Result: The effectiveness of observation group was 93.75%, better than the control group with 77.08%(P<0.05). Each domain and overall items of ACT of observation group were higher than the control group (P<0.01). The improvement of lung function (FEV₁, FVC, PEF) of the experimental group was better than of the control group (P<0.01). Asthma symptoms of daytime and nighttime symptom score rating of the experimental group was lower than that of the control group (P<0.01). The St. George's Respiratory Questionnaire (SGRQ) scores of the experimental group, were significantly decreased and lower than that of the control group (P<0.01). The scores of Lung and kidney Qi deficiency with Cold phlegm syndrome were lower than the control group (P<0.01). Conclusion: Guben Pingchuan decoction improves the clinical curative effect and patients life quality of chronicity-persistent period in bronchial asthmaand deserves promotion.