Literature Review of Transdermal Absorption in Ginsenoside Rg1 from Notoginseng Radix et Rhizoma

Abstract:

As the ever-accelerated discovering of ginsenoside Rg₁' s pharmacological activities and updating of traditional chinese medicine percutaneous preparation, recent relevant references and information were summarized, and further analyzed and reviewed in this paper. Research conditions of transdermal absorption in ginsenoside Rg₁ was summarized briefly, which generally included choices of cutaneous penetration, influence factors of transdermal absorption and penetration enhancers. The results showed that ginsenoside Rg₁ has a certain transdermal performance.Factors affecting its transdermal are numerous, which the matrix is selected as the decisive factor. Development and selection of different chemical, medicine and composite penetration enhancers to improve ginsenoside Rg₁'s transdermal performance are significant.Transdermal absorption of ginsenoside Rg₁ will provided reasonable theoretical basis for its new transdermal preparations and clinical application.