Relationship between Matrix Metalloproteinase and AS Vascular Remodeling and Reversal Effect of Traditional Chinese Medicine

Abstract:

Atherosclerosis is a common pathological basis of cardiovascular disease.The pathological changes of smooth muscle cell and extracellular matrix metalloproteinases led to vascular remodeling.The key factors of causing and maintaining atherosclerosis plaque vulnerability.Matrix metalloproteinases play an important role. This article reviews the biological characteristics and pathogenic mechanism of matrix metalloproteinases and the reversal effect of traditional Chinese medicine(TCM) in order to provide help to search for effective TCM of atherosclerosis.