Abstract:Objective: To optimize processing technology of Saposhnikoviae Radix. Method: Taking composite score of contents of prim-O-glucosylcimifugin and 5-O-methylvisammioside,extract yield,water contents as index,effects of slice thickness,drying time and drying temperature on pieces quality were investigated by Box-Behnken design-response surface methodology,so as to optimize processing technology parameters of Saposhnikoviae Radix. Result: Optimal processing parameters were as follows:slice thickness 3-4 mm,drying temperature at 60 ℃,drying time 2 hours.Under these conditions,contents of prim-O-glucosylcimifugin and 5-O-methylvisammioside,extract yield,water contents were 0.917%,0.054%,20.45% and 5.110%,respectively. Conclusion: Optimized processing technology for Saposhnikoviae Radix was feasible and reasonable,it could provide a reference for quality control of Saposhnikoviae Radix pieces.