Stability of Icariside and Factors Affecting the Stability

Abstract:

Objective: To analyze and determine the stability of icariside and its factors affecting in different conditions. Method: On the basis of ultraviolet-visible spectrum under 200-600 nm region scan, determine the factors affecting the chemical structure of icariside in different conditions. Result: Icariside was stable in water, incruding slightly acidic, basic and neutral conditions.When it existed in aqueous phase under pH<2 or pH>10 conditions, the chemical structure of icariside was changed. Furthermore, its aqueous phase under 100 ℃ for a long time was remain stable. In the processes of extracting and using icariside, metal ion such as Cu²⁺, Fe³⁺and Al³⁺ should be wiped off, as they were able to chelate with icariside, and could induce oxidation as well. Conclusion: Using ultraviolet-visible spectrum can primary observation the factors affecting the stability of icariside in different conditions, and providing important information on its extraction, preparation and derivatives preparation.