Pentacyclic Triterpenoids from Spiraea pubescens (Ⅱ)

Abstract:

Objective: To further investigate the chemical constituents from the petroleum ether and chloroform fractions of ethanol extract from Spiraea pubescens. Method: The compounds were isolated by silica gel chromatography, ODS chromatography, and preparative HPLC,and their structures were elucidated on the basis of chemical and spectroscopic methods,including MS,1D and 2D NMR spectral techniques. Result: Nine compounds were isolated from the petroleum ether and chloroform fractions of ethanol extract from S. pubescens,and were identified as ursolic acid (1), ursolic aldehyde (2), ursonic acid (3), germanicol (4), α-amyrenol (5), erythrodiol (6), betulinic acid (7), oleanolic acid (8), and betulonic acid (9). Conclusion: This is the first report of the isolation of 2-6 and 8-9 from Spiraea genus,and 1, 7 from this plant.