Abstract:Objective: Antioxidative activities of different polarity parts in extracts with ethanol from Hyssopus cuspidatus and Nepeta bracteata were studied in vitro. Method: In vitro chemical simulation conditions, the antioxidant properties of different parts in ethanol extracts of H. cuspidatus and N. bracteata were evaluated by different antioxidant tests, including 1, 1 diphenyl-2-bitter hydrazo (DPPH·) and (O2-·) free radical scavenging ability, pyrogallol autoxidation and iron ion reduction. Result: The different polarity parts in extracts with ethanol from the two medicinal materials all have free radical scavenging and reduction abilities to some extent. Conclusion: H. cuspidatus and N. bracteata have antioxidant activities, which will supply the separating base of antioxidative components from them in further research.