Influence of Borneol on Neurotransmitters：a Systematic Review of Relevant Basic Research

Abstract:

Objective: To systematic review the basic research's about the effect of borneol on neurotransmitters. Method: We searched Pub Med (1996 to 2012), VIP (1989 to 2012), Wan Fang Database (1990 to 2012), CNKI (1979 to 2012), and collected basic research literature related to borneol's impacts on neurotransmitter. The publications were screened, assessed and extracted valid data based on predetermined criteria. Result: A total of 11 basic researches were identified,found that borneol have a certain influence on content of monoamine, amino acids, beta-endorphin in central nervous system and catecholamine peripheral, and the outcome was related to the dose, the modeling methods, drawn parts, drawn time. One study showed that the central acetylcholine content have no difference between the experimental group and the control. Conclusion: Because of the researches obtain different methods, models, administration, the results are not uniform, difficult to prove each other, and the methodology and research system needs to be further strengthened.