Abstract:Objective: The discuss the influence on patients' living quality and progression free survival of Fuzheng Huadu decoction to treat non-small cell lung cancer(NSCLC) in the middle and late period after chemotherapy. Method: Eighty-five cases of patients with NSCLC were randomly divided into control group (42 cases) and observation group (43 cases)according to hospital admission order.The patients in control group used symptomatic and supportive treatment.The patients in the observation group plus Fuzheng Huadu decoction on the basis of control group treatment. Until their disease appeared terminate the observation.Adopt European organization research and treatment of cancer quality of life(EORTCQLQ-C30).Conduct therapy KPS grade.Record progression free survival(PFS).Detect T cell subset (CD3+, CD4+, CD8+, CD4+/CD8+)and lmmunoglobulin detection(IgG, IgA, IgM). Result: After treatment, for the observation group the scores of physical performance, role function, emotional function, society function and global quality of life were superior to that of the control group(P<0.01). As for the scores of tired, nausea and vomit, dyspnea, insomnia and the loss of appetite were lower than that of the control group(P<0.01). Karnofsky rate (increasing+stable) was 90.70% superior to 71.43% of the control group71.43%(P<0.05). And the progression free survival of the observation group was (7.3±0.85)mouths superior to (4.5±1.08) of the control group(P<0.01). And compared with the index before treatment, CD3+, CD4+, CD8+, CD4+/CD8+ and IgG all improved which were higher than that of the control group(P<0.01). Conclusion: The maintenance treatment of Fuzheng Huadu decoction can improve the quality of life of patients when it was used in non small cell lung cancer, after chemotherapy and lengthen PFS, improve immune function.
