New Progression of Chinese Medicine Nanoparticles Drug Delivery System in Hepatocellular Carcinoma

Abstract:

In this paper, We performed a analysis andsummaryof numerous published papers about Chinese medicine NPs'targeted therapy in Hepatocellular carcinoma( HCC)from three aspects: focusing on the passive targeting, active targeting and physicochemical targetingagents, especially the mechanisms and methods. We also give a discussion and outlook about the further development of Chinese medicine NPs'drug delivery systems in HCC. (HCC) is a kind of malignancy with high morbidity and mortality, Due to the drug' poor selectivity to tumor, low absorption and the emergence of multidrug resistance clinically, the effect of chemotherapy in patients with liver cancer is not ideal. Where the chinese medicine play a significant role, The chinese medicine nanoparticles(NPs) combineing the advantages of nano-medicine and nano-medicine, solve the above problems effectively , show a wealth of potential applications in the treatment of liver cancer, and become the hot spot in HCC targeted therapy nowadays.