Abstract:Objective: Taking decarburization fluid of Reduning injection as research object,to compare applicability of three kinds of membrane modules for membrane filtration of Reduning injection. Method: Hollow fibre,plate and roll type of membrane module was selected for ultrafiltration,taking membrane flux,transfer rates of index ingredients (gardenoside and chlorogenic acid) before and after ultrafiltration,fingerprint similarity,solid content decrement,protein,color comparison,oxalic acid salt and resin as indexes,membrane filtration effect of 3 kinds of membrane modules on Reduning injection was compared. Result: Three kinds of membrane modules existed differences on applicability of the same liquid system,membrane flux of plate type of membrane module was maximum,hollow fiber membrane module was minimum.Transmittances of gardenoside with hollow fiber,plate,roll type of membrane module were 87.53%,91.76% and 89.41%,transmittances of chlorogenic acid were 86.46%,91.23% and 89.47%,fingerprint similarity were 0.992,0.995 and 0.999,reduction rates of solid content were 21.35%,18.64% and 17.53%,liquid color from 8 into 3,4 and 5,respectively. Conclusion: In reduction rates of solid content and degree of clarity improvement,hollow fiber and plate type of membranes have advantages by camparing with roll type of membrane.Three types of membrane modules are suitable for ultrafiltration of decarburization fluid of Reduning injection,which best plate type of membrane.