Fast Pesticide Multiresidue Analysis in Panax Ginseng Extract by Gas Chromatography Mass Spectrometry with QuEChERS

Abstract:

Objective: To establish the chromatographic method for rapid determination of 25 pesticide residues in Ginseng extract by QuEChERS-GC-MS. Method: The samples were extracted with acetone which included acetonitrile,the sodium chloride,anhydrous magnesium sulfate salting out process,and cleaned up by PSA and GCB,and reduced the matrix effect by Matrix matched standard curve method. Result: The endrin aldehyde, p, p'-DDT,methoxychlor showed relatively strong matrix effects(ME >130%),and parathion showed strong matrix effects (ME >150%),after the correction of matrix calibration curve,the linear range was 0.01-1 mg·L^-1 and r >0.995 4,the recovery range was 81.8%-110.7% in 3 adding level (0.1,0.5,1.0 μg·g^-1), RSD<15%,LOQ was 3-48 μg·kg^-1. Conclusion: The method is accurate, sensitive and suitable for the determination of pesticide residues in ginseng extract.