Meta-analysis of Integrated Traditional Chinese and Western Medicine in Treating Menopause Hypertension

Abstract:

Objective: The aim of this study was to compare the clinical efficacy of integration of traditional Chinese medicine(TCM) and western medicine, and the western medicine therapy for menopause hypertension. Method: The randomized controlled trials were collected via searching the internet. The literatures were screened according to inclusion and exclusion criteria. All the assignments were performed by two researchers. If there was disagreement between the two researchers, we would ask evidence based medicine expert for advice, to get an optimal result.The database included the ChianInfo(1978—2014), the Superstar database(1955—2014), the CBM(1985—2014), CNKI(1984—2014), VIP(1989—2014), PubMed(1966—2014), EMbase(1984—2014), OVID, Springer Linker(1997—2014)and Science Direct(1998—2014).According to Meta analysis, the RevMan 5.2 software was used to recover and analyze the literatures, and make the assessment of the integration of TCM and western medicine in treating the women with menopause hypertension. Result: In the study, 23 trials were included. The total number of cases is 1969.The Meta analysis results showed that:Compared with western medicine, the integration of TCM and western medicine would lower blood pressure[OR=3.83,95%CI (2.74,5.37), P=0.68], improve the climacteric symptom:[OR=3.41,95%CI(22.14,5.42), P=0.77]. Conclusion: The Integration of traditional Chinese medicine and western medicine could improve the menopause hypertension symptom, lower blood pressure. All the curative effects are better than western medicine.