Recent Progress of Drug Nature of Coptidis Rhizoma

Abstract:

Drug nature of Coptidis Rhizoma was reviewed in the paper which provided a new idea for research on drug nature.It is difficult to find a suitable research subject for discussing nature of Coptidis Rhizomaalthough some subjects were adopted in many researches. Some studies demonstrated that Coptidis Rhizoma, in a way, was a cold-natured medicine. However, it is still a long way to establish a criterion of cold-natured medicine. The emergency of interdiscipline may open a new door for exploring drug nature of Coptidis Rhizoma in the future. Epigenetic modifications, such as DNA methylation/demethylation, chromatin remodeling and histone modification, often change along with both inner and outer environment. Coptidis Rhizoma as an outer environmental factor may reversely regulate epigenetic modifications which are caused by diseases. Therefore, epigenetics may provide a new field in researches of drug nature ofCoptidis Rhizoma in the future.