Abstract:After posterior pituitary hormone(0.5 U/kg)and propanolol(5 mg/kg)were injected through external jugular vein cannula in rats,abnormal ECG changes appeared,which included raised S-T segment,peaked T wave,accelerated heart rate,depressed QRS spike.Hongjingtian Capsule could effectively prevent the above-mentioned ECG changes in experimental animals,which suggested that the capsule had preventive effect on the acute myocardial ischemia with heart failure.