寒感安发汗止咳平喘药理作用实验研究

Experimental Studies on Pharmacological Effects of Hanganan on Inducing Sweat,Relieving Cough and Subduing Asthma

摘要:

寒感安在多种动物模型中有平喘、止咳和发汗作用。对豚鼠药物性哮喘和离体肺灌流量减少均有明显对抗作用，对氨水所致小白鼠的咳嗽有明显的抑制作用，可明显地抑制大白鼠足跖汗腺和小鼠汗腺的分泌。

Abstract:

Hanganan (HGA) was orally given and had effects of subduing asthma,relieving cough and inducing sweat in multiple animal models.The experimental results showed that HGA could obviously produce a protective effect on the bronchial asthma induced by inhalation of histamine in conscious guinea-pigs,and inhibit the decrease of pulmonary perfusion flow in isolated lung of guinea-pigs and the cough induced by ammonia water.Also it could markedly inhibit the secretion of sweat gland in rats and mice.