虎金丸对CCl4所致实验性肝损伤的保护作用

Protective Effect of Hujin Pills on CCl4-induced Experimental Liver Injury

摘要:

虎金丸ig小鼠,能显著降低CCl₄所致血中ALT?AST?GST和肝中MDA水平的升高;虎金丸ig大鼠制得药物血清后,以10%浓度加入原代培养大鼠肝细胞培养液中,能显著降低10mmol/L CCl₄所致培养液中ALT和MDA的升高,并使细胞存活率由55.90%提高至82.45%?

Abstract:

After the mice were dosed with Hujin Pill for 6 days,the raised level of ALT,AST,GST in serum and MDA in liver caused by CCl₄ was ameliorated evidently.In addition,for primay cultured rat hepatocytes,rat serum containing Hujin Pills could remarkably decrease the raised level of ALT and MDA in the culture caused by 10 mmol/L CCl₄,and the cell viability was improved from 55.90% to 82.45%.