冠心康对实验性高脂血症及血液流变学的影响

Effects of Guanxinkang Granule on Experimental Hyperlipemia and Hemorrheology

摘要:

探讨冠心康颗粒剂对小鼠实验性高脂血症及大鼠血液流变学的影响,结果表明冠心康能明显抑制Triton WR-1339所致小鼠TG?TC的升高,增强血瘀大鼠红细胞变形能力,降低全血比粘度和血浆比粘度,降低五羟色胺的含量,同时还显著扩张正常小鼠微血管。

Abstract:

Effects of guanxinkang granule(GG)on experimental hyperlipemia in mice and hemorrheology in rats were studied.The results showed that GG could remarkably lower the increased of serum TC and TG levels induced by Triton WR-1339.As for the rats with blood stasis,GG was observed to possess remarkable enhancing effects on erythrocyte deformability,decrease ηB、ηP,and lower the level of 5-HT.In addition,GG could significantly dilate micrangium and improve blood flow rate in normal mice.