当归补血汤及其含药血清对小鼠红系造血祖细胞克隆的影响

Effect of Danggui Buxue Decoction and the Decoction-contained Serum onErythroid Progenitor Cell Colony Forming Unit(CFU-E) in Mice

摘要:

当归补血汤水煎液不能刺激红系造血祖细胞(CFU-E)的增殖,而含药血清有促进CFU-E增殖的作用,随含药血清量的增加,CFU-E克隆增殖数增高,与正常对照血清有明显差别?同法取拆方与合方口饲小鼠的含药血清,观察CFU-E(3d)?BFU-E(7d)克隆增殖情况?各药促进CFU-E?BFU-E克隆增殖的平均数值顺序是黄芪血清组>归芪1∶5血清组>归芪1∶1血清组>当归血清组>空白小鼠血清组?

Abstract:

Danggui Buxue Decoction did not directly stimulate reproduction of CFU-E in vitro,but the decoction-contained serum could has the effect with a obvious distinction compared with normal control serum.The quantity of CFU-E was promoted with increasing the serum dosage.The serum containing the separated formulae could stimulate reproduction of CFU-E,respectively.The proper sequence of the stimulating effect was as follows:Huang Qi>Danggui and Huang Qi(1:5)>Danggui and Huang Qi(1:1)>Danggui>normal control serum.