五虎汤止咳平喘作用的实验研究

Antitussive and Antiasthmatic Action of Wu-Hu-Tang

摘要:

五虎汤冻干粉明显延长小鼠二氧化硫引咳和豚鼠枸橼酸引咳的潜伏期,减少枸橼酸引咳的次数,促进小鼠气管、支气管对酚红的排泄,并显著延长组胺——乙酰胆碱混合液诱导豚鼠哮喘发作的潜伏期,提示五虎汤具有止咳、平喘、化痰的作用。

Abstract:

Freeze-dred powder of Wu-Hu-Tang markedly prolonged the latent period of cough induced by sulfur dioxide in mice,prolonged the latent period of cough and decreased the cough frequency induced by citric acid in guinea pigs,increased the secretion of phenol red from the airway and subairway in-mice,significantly prolonged the latent period of asthmatic attack by mixture of histamine-acetylcholine in guinea pigs.These results indicated the Wu-Hu-Tang had antitussive、antiasthmatic and phlegm-idissiped action.