中药质量控制面临的问题及其研究

Discussion on the Problem of Quality Control of Chinese Drugs

摘要:

从中医复方物质基础研究的角度,对现行的以复方中主要药味的成分含量来评价和规范中药的质量标准提出质疑。指出在复方化学意义上,认识特定药效条件下复方物质间的关系是确定中药质量标准的先决条件;中药是中医理论指导下的产物,应建立具有中医药特色、符合临床实际的中药质控标准体系;中药的化学质控不仅要借助先进分析技术手段,也要遵循中医“方(药)证相关”的逻辑和现代“病证结合”的思路。

Abstract:

The quality control system of Chinese compound priscription and routine evaluation methods are to control the content of major ingredients in the prescription.It is not prefect from the point of chemical substances.The ratio relationship among components related to certain pharmacological effects in prescription should be considered in the quality evaluatuion of Chinese compound prescription.The quality evaluation system of Chinese drugs,which were used accoding to the guidance of TCM theory,should accord with clinical practice of TCM,i.g. follow the logic of correlativity between prescription or drug and syndrome treated,and the integrated analysis based on modern disease and traditional syndrome.