川贝枇杷膏止咳、化痰、平喘、抗炎及免疫作用研究

Study on the Pharmacodynamic of ChuanBeiPipa Confection

摘要:

目的:考察川贝枇杷膏的主要药效。方法:通过浓氨水喷雾实验、二氧化硫刺激法、毛细玻管法、喷雾致喘法、蛋清性足肿胀法以及测量免疫器官重量等实验,观察川贝枇杷膏在止咳、化痰、平喘、抗炎及免疫方面的药效。结果:川贝枇杷膏可以延长小鼠咳嗽的潜伏期,增加大鼠痰液的分泌量,延长豚鼠哮喘的潜伏期,减小大鼠足肿胀度,此外,小鼠的胸腺指数和脾脏指数均明显升高。结论:川贝枇杷膏具有显著的止咳、化痰、平喘、抗炎及免疫作用。

Abstract:

Objective To study the pharmacological effects of ChuanBeiPipa Confection.Methods The anti-tussive,anti-asthmatic and expectorant effects were observed by concentrated ammonia method in mice,spray method in cavies and capillary method in mice. Results ChuanBeiPipa Confection had inhibitory effect on cough caused by concentrated ammonia in mice,prolonged the latency of cough,decreased the frequency of cough,and increased the secretion of expectoration.The confection also had the significant inhibitory effects on asthma in cavies. Couclusion ChuanBeiPipa Confection has anti-tussive,anti-asthmatic and expectorant effects.