复方灵芝降糖胶囊对Ⅱ型糖尿病大鼠相关指标的影响

The Effect of Co-lingzhijiangtang Capsule to the Glucose,Lipid and SOD-activity in Blood of Type Ⅱ Melituria Rats

摘要:

目的:观察复方灵芝降糖胶囊对Ⅱ型糖尿病模型大鼠的作用。方法:以高脂饲料喂饲Wistar大鼠诱发胰岛素抵抗,并以小剂量链尿佐菌素(STZ)ip,诱发Ⅱ型糖尿病。模型大鼠随机分组,ig给药。给药结束后取血进行血糖、甘油三酯(TG)、胆固醇(TC)、超氧化物歧化酶(SOD)检测。结果:与模型组相比,复方灵芝降糖胶囊高,中,低剂量给药1个月后糖尿病大鼠血糖、TG、TC均明显下降,SOD值明显升高,统计学具显著意义。结论:复方灵芝降糖胶囊对大鼠Ⅱ型糖尿病模型有较好的疗效。

Abstract:

Objective:To study the effect of Co-Lingzhi jiangtang Capsule to type Ⅱ melituria rats. Method: To make the model of type Ⅱ melituria rats with feeding hyper-lipid fodder and injecting a small dosage STZ to intraperitoneum.And then the modle rats were divided into 7 groups and administered.After administration the blood samples were taken to determine their blood glucose,TG,TC,and SOD.Results: Compareing to control group,the capsule has obvious effects on lowering blood glucose,TG and TC and enhanceing SOD-activity after administration for 1 month.Conclusion: The Co-Lingzhijiangtang Capsule may be an effective medicine to treat type Ⅱ diabetes mellitus.